The cost reduction applies to minion cards, they are also played by the Methuselah.
102244
The Shard, London
Unique location.
If you have the Edge, you can lock this card to reduce the cost of a card you play by 2 pool or blood. Vampires can steal this location as a Ⓓ action; Ventrue get +1 stealth during that action.
Rulings
Can allow allies to play cards that otherwise cost blood (eg. Procurer), if they do not otherwise require a vampire (eg. clan or discipline).
Can be locked to reduce the cost at any point before resolution, from when the action is announced to just before the cost is paid. If it is used when announcing an action, and the action is cancelled as played (e.g. Direct Intervention), it is not locked.
Can reduce the cost of an action card even if it is not played as an action (e.g. a weapon played with Concealed Weapon or an Ally with Piper).
Allows to play a card that could otherwise not be afforded, in which case, it must be locked when the action is announced.